MCAT Question of the Day
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    Q:

    		 A contentious issue in stem cell biology is whether mesenchymal stem cells differentiate into cartilage, bone, and fat tissue in vivo or if those effects are only seen in vitro. How might researchers design an experiment to confirm in vivo differentiation?
    		 

    A

    		 Inject a mouse with labeled mesenchymal stem cells that have been cultured in vitro and track the label at common sites of differentiation.

    B

    		 Treat mice with a drug that targets mesenchymal stem cells and measure the production of bone, cartilage, and fat tissues.

    C

    		 Mutate a line of mice to produce a label on their mesenchymal stem cells, and track the activity of the cells at common sites of differentiation.

    D

    		 Track the population of mesenchymal stem cells in mice as they age and begin to produce less bone, cartilage, and fat tissue.



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