MCAT Question of the Day


  • Q:

    Ibuprofen has both an (R) and an (S) set of enantiomers, with the (S) form being the pharmacologically active form of the drug. In studies, scientists attempted to optimize the effectiveness of the drug by administering only the (S) form, but found no significant improvements in drug efficiency. Which of the following best explains the findings?

     

    A

    The (R) enantiomer is pharmacologically active through another pathway.

    B

    There is a maximum amount of (S) enantiomer that can be administered at any given time before the addition of more drug ceases to have an effect.

    C

    An enzyme exists which catalyzes the conversion of the (R) to the (S) isomer in vivo.

    D

    The enantiomers do not racemize when in solution.



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